Percutaneous transhepatic or endoscopic ultrasound-guided biliary drainage in malignant distal bile duct obstruction using a self-expanding metal stent: Study protocol for a prospective European multicenter trial (PUMa trial).

BackgroundEndoscopic ultrasound-guided biliary drainage (EUS-BD) was associated with better clinical success and a lower rate of adverse events (AEs) than fluoroscopy-guided percutaneous transhepatic biliary drainage (PTBD) in recent single center studies with mainly retrospective design and small case numbers (MethodsThe study is designed as a non

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Parent, patient and clinician perceptions of outcomes during and following neonatal care: a systematic review of qualitative research

Objective Multiple outcomes can be measured in infants that receive neonatal care.It is unknown whether outcomes of importance to parents and patients differ from those of health professionals.Our objective was to systematically map neonatal care outcomes discussed in qualitative research by patients, parents and healthcare professionals and test w

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Role of Insulin-Like Growth Factor Receptor 2 across Muscle Homeostasis: Implications for Treating Muscular Dystrophy

The insulin-like growth factor 2 receptor (IGF2R) plays a major role in binding and regulating the circulating and tissue levels of the mitogenic peptide insulin-like growth Ball - Catcher - Leg Guard factor 2 (IGF2).IGF2/IGF2R interaction influences cell growth, survival, and migration in normal tissue development, and the deregulation of IGF2R ex

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